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cis-Vaccenic acid

CAS No. 506-17-2

cis-Vaccenic acid( —— )

Catalog No. M35277 CAS No. 506-17-2

cis-Vaccenic acid (Asclepic acid) is the antiviral extract from Rhodopseudomonas capsulate and the predominant active component of Rhodopseudomonas capsulate. cis-Vaccenic acid acts a potential fetal hemoglobin inducer.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    cis-Vaccenic acid
  • Note
    Research use only, not for human use.
  • Brief Description
    cis-Vaccenic acid (Asclepic acid) is the antiviral extract from Rhodopseudomonas capsulate and the predominant active component of Rhodopseudomonas capsulate. cis-Vaccenic acid acts a potential fetal hemoglobin inducer.
  • Description
    cis-Vaccenic acid, the antiviral extract from Rhodopseudomonas capsulate and the predominant active component of Rhodopseudomonas capsulate, acts a potential fetal hemoglobin inducer.
  • In Vitro
    cis-Vaccenic acid (CVA) (50 μM, 70 μM and 100 μM) induces differentiation and up-regulates gamma globin synthesis in K562, JK1 and transgenic mice erythroid progenitor stem cells. cis-Vaccenic acid (50 μM) also increased the percentage of benzidine positive JK-1 cell.Cell Differentiation Assay Cell Line:K562 cells Concentration:50 μM, 70 μM and 100 μM Incubation Time:48 and 120 hours Result:Induced differentiation appeared to be concentration dependent in K562 cells with 50 μM CVA being the most effective concentration with more than 20% of the K562 cells showing positive for Benzidine stain after 48 h of incubation with CVA.
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Immunology/Inflammation
  • Target
    Antiviral
  • Recptor
    Antiviral
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    506-17-2
  • Formula Weight
    282.46
  • Molecular Formula
    C18H34O2
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : ≥ 50 mg/mL (177.02 mM )
  • SMILES
    C(CCC/C=C\CCCCCC)CCCCCC(O)=O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. H Hirotani, et al. Inactivation of T5 phage by cis-vaccenic acid, an antivirus substance from Rhodopseudomonas capsulata, and by unsaturated fatty acids and related alcohols. FEMS Microbiol Lett. 1991 Jan 1;61(1):13-7.?
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