Pascolizumab( —— )

Catalog No. M36890 CAS No. 331243-22-2

Pascolizumab (SB-240683) is a humanized monoclonal antibody targeting IL-4, exhibiting asthmatic effects and useful for studying allergic rhinitis.

Purity : >98% (HPLC)

COA

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HPLC

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Biological Information

Product Name

Pascolizumab
Note

Research use only, not for human use.
Brief Description

Pascolizumab (SB-240683) is a humanized monoclonal antibody targeting IL-4, exhibiting asthmatic effects and useful for studying allergic rhinitis.
Description

Pascolizumab (SB-240683) is a humanized anti-IL-4 monoclonal antibody. Pascolizumab has the potential for the research of asthma.
In Vitro

Cell Proliferation Assay Cell Line:human or monkey T cells Concentration:0-10000 pM Incubation Time:3 days Result:Inhibited the response of human and monkey T cells to recombinant monkey IL-4 (2 ng/ml) with IC50 values of 268 pM and 587 pM, respectively.
In Vivo

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Synonyms

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Pathway

Apoptosis
Target

IL Receptor
Recptor

IL Receptor
Research Area

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Indication

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Chemical Information

CAS Number

331243-22-2
Formula Weight
Molecular Formula

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Purity

>98% (HPLC)
Solubility

——
SMILES

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Chemical Name

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Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. Hart TK, et al. Preclinical efficacy and safety of pascolizumab (SB 240683): a humanized anti-interleukin-4 antibody with therapeutic potential in asthma. Clin Exp Immunol. 2002 Oct;130(1):93-100.?

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