Cart
sales@molnova.com
PDM2
CAS No. 688348-25-6
PDM2( —— )
Catalog No. M18999 CAS No. 688348-25-6
PDM 2 is a potent and selective aryl hydrocarbon receptor (AhR) antagonist.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 10MG | 38 | In Stock |
|
| 25MG | 71 | In Stock |
|
| 50MG | 114 | In Stock |
|
| 100MG | 206 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NamePDM2
-
NoteResearch use only, not for human use.
-
Brief DescriptionPDM 2 is a potent and selective aryl hydrocarbon receptor (AhR) antagonist.
-
DescriptionPDM 2 is a potent and selective aryl hydrocarbon receptor (AhR) antagonist.
-
In VitroPDM2 (Compound 4b) exhibits a Ki of 1.2±0.4 nM for AhR and no affinity for estrogen receptor (ER), confirming that replacement of hydroxyl with chloride abolished binding on ER and increased dramatically the affinity for AhR.
-
In Vivo——
-
Synonyms——
-
PathwayMetabolic Enzyme/Protease
-
TargetFAAH
-
RecptorAhR
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number688348-25-6
-
Formula Weight283.58
-
Molecular FormulaC14H9Cl3
-
Purity>98% (HPLC)
-
SolubilityDMSO : 50 mg/mL 176.32 mM
-
SMILESClc1ccc(cc1)\C=C\c1cc(Cl)cc(Cl)c1
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1.de Medina, P. ,Casper, R.,Savouret, J.F., et al. Journal of Medicinal Chemistry 48, 287-291 (2005).
molnova catalog
related products
-
PF 750
PF 750 is a selective and covalent inhibitor of FAAH. PF 750 shows IC50s varying from 16.2 to 595 nM in different incubation times.
-
AP-III-a4
AP-III-a4 (ENOblock) is the first nonsubstrate analogue inhibitor of enolase with IC50 of 0.576 μM.
-
PF-3845
PF-3845 is a potent, selective and irreversible FAAH inhibitor with Ki of 230 nM, showing negligible activity against FAAH2.
