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Nidanilimab
CAS No. 2171061-85-9
Nidanilimab( —— )
Catalog No. M36753 CAS No. 2171061-85-9
Nidanilimab (CAN04) is a fully humanized IL1RAP monoclonal antibody with a Kd value of 1.10 pM. It exhibits antitumor activity by disrupting the IL1α and IL1β signaling pathways and inducing the immune system to destroy tumor cells.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 369 | Get Quote |
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| 5MG | 715 | Get Quote |
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| 10MG | 1121 | Get Quote |
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| 25MG | 1610 | Get Quote |
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| 50MG | 2162 | Get Quote |
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| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
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Biological Information
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Product NameNidanilimab
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NoteResearch use only, not for human use.
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Brief DescriptionNidanilimab (CAN04) is a fully humanized IL1RAP monoclonal antibody with a Kd value of 1.10 pM. It exhibits antitumor activity by disrupting the IL1α and IL1β signaling pathways and inducing the immune system to destroy tumor cells.
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DescriptionNidanilimab (CAN04) is a fully humanized monoclonal anti-IL1RAP antibody with a Kd value of 1.10 pM. Nidanilimab blocks IL1α and IL1β signaling and stimulates the immune system to destroy tumour cells. Nidanilimab can be used in research of non-small lung cancer (NSCLC) and pancreatic ductal adenocarcinoma (PDAC) .
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In Vitro——
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In VivoAnimal Model:Nude C57Bl/6 mice with LU2503 NSCLC PDX model Dosage:10 mg/kg Administration:Intraperitoneal injection Result:Displayed a significantly stronger anti-tumor effect compared to isotype control with chemotherapy.
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Synonyms——
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PathwayApoptosis
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TargetIL Receptor
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RecptorIL Receptor
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Research Area——
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Indication——
Chemical Information
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CAS Number2171061-85-9
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Formula Weight
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Molecular Formula——
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Purity>98% (HPLC)
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Solubility——
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SMILES——
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Millrud CR, et, al. The anti-IL1RAP antibody CAN04 increases tumor sensitivity to platinum-based chemotherapy.
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