NOC-5( —— )

Catalog No. M34805 CAS No. 146724-82-5

NOC-5 is an NO donor that induces airway relaxation and concentration-dependently triggers 10 μM DAF-2 fluorescence.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

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Biological Information

Product Name

NOC-5
Note

Research use only, not for human use.
Brief Description

NOC-5 is an NO donor that induces airway relaxation and concentration-dependently triggers 10 μM DAF-2 fluorescence.
Description

NOC-5 is a diazeniumdiolate compound that belongs to the same family of NO donors.
In Vitro

NOC-5 (5-20 μM) in PBS led to a rapid increase in NO release on day one.NOC-5 (100 μM, 24 h) activates only caspase-3; an increase in caspase-3 activity occurred after NO donor treatment: 1.62 (1.57-1.66) (P < 0.05). NOC-5 has pro-apoptotic action in Jurkat cells, but at the same time increased the level of anti-apoptotic proteins.
In Vivo

——
Synonyms

——
Pathway

Immunology/Inflammation
Target

NOS
Recptor

NO Synthase
Research Area

——
Indication

——

Chemical Information

CAS Number

146724-82-5
Formula Weight

176.22
Molecular Formula

C6H16N4O2
Purity

>98% (HPLC)
Solubility

——
SMILES

O=NN(O)N(CCCN)C(C)C
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. Sophie A Bradley, et al. Characterisation and comparison of temporal release profiles of nitric oxide generating donors. J Neurosci Methods. 2015 Apr 30;245:116-24.?

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