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NLRP3-IN-13

CAS No. 1704638-35-6

NLRP3-IN-13( —— )

Catalog No. M36488 CAS No. 1704638-35-6

NLRP3-IN-13 is a selective NLRP3 inhibitor that inhibits NLRP3-associated inflammation.NLRP3-IN-13 can be used in the study of neurological disorders and inflammation.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

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5MG	117	In Stock
10MG	188	In Stock
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Biological Information

Product Name

NLRP3-IN-13
Note

Research use only, not for human use.
Brief Description

NLRP3-IN-13 is a selective NLRP3 inhibitor that inhibits NLRP3-associated inflammation.NLRP3-IN-13 can be used in the study of neurological disorders and inflammation.
Description

NLRP3-IN-13 (Compound C77 in reference patent) is a selective and potent NLRP3 inhibitor (IC50: 2.1 μM). NLRP3-IN-13 inhibits NLRP3 andNLRC4 inflammasomes, and inhibits NLRP3-mediated IL-1β production. NLRP3-IN-13 also inhibits NLRP3 ATPase activity. NLRP3-IN-13 can be used in the research of neuroinflammatory disorders.
In Vitro

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In Vivo

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Synonyms

——
Pathway

NF-κB
Target

NOD
Recptor

NOD
Research Area

——
Indication

——

Chemical Information

CAS Number

1704638-35-6
Formula Weight

365.41
Molecular Formula

C19H15N3O3S
Purity

>98% (HPLC)
Solubility

In Vitro:?DMSO : 50 mg/mL (136.83 mM; Ultrasonic )
SMILES

O=C1OC=2C=CC=CC2N1CC(=O)NCC3=CN=CC(=C3)C4=CSC=C4
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. Devita Robert, et al. Benzoxazolones as inhibitors of inflammasomes and their preparation. Patent. WO2022187804.

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