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NLRP3-IN-11

CAS No. 2769040-91-5

NLRP3-IN-11( —— )

Catalog No. M35514 CAS No. 2769040-91-5

NLRP3-IN-11 is an NLRP3 protein inhibitor with potential anti-inflammatory activity.NLRP3-IN-11 can be used in the study of atherosclerosis and parkinsonism.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    NLRP3-IN-11
  • Note
    Research use only, not for human use.
  • Brief Description
    NLRP3-IN-11 is an NLRP3 protein inhibitor with potential anti-inflammatory activity.NLRP3-IN-11 can be used in the study of atherosclerosis and parkinsonism.
  • Description
    NLRP3-IN-11 is a NLR family pyrin domain containing 3 (NLRP3) proteins inhibitor. NLRP3-IN-11 has biological activity for NLRP3 with an IC50 value of <0.3 μM. NLRP3-IN-11 can be used for the researh of inflammatory and degenerative diseases including NASH, atherosclerosis and other cardiovascular diseases, Alzheimer's disease, Parkinson's disease, diabetes, gout, and numerous other autoinflammatory diseases.
  • In Vitro
    NLRP3-IN-11 has biological activity with an IC50 value of <0.3 μM in human PBMC NLRP3 assay.
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    NF-κB
  • Target
    NOD
  • Recptor
    NOD
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    2769040-91-5
  • Formula Weight
    344.8
  • Molecular Formula
    C17H17ClN4O2
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 125 mg/mL (362.53 mM; Ultrasonic )
  • SMILES
    N(CC(C)(C)O)C=1C2=C(C(=NN1)C3=C(O)C=C(Cl)C=C3)C=CN=C2
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.HY-W048205, et al. Compounds for inhibiting NLRP3 and uses thereof. Patent. US11319319B1.
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