Cart
sales@molnova.com
N-desmethyl Olanzapine
CAS No. 161696-76-0
N-desmethyl Olanzapine( —— )
Catalog No. M34784 CAS No. 161696-76-0
N-desmethyl Olanzapine is a metabolite of the atypical antipsychotic compound Olanzapinec, which is formed through the oxidative metabolism of olanzapine by the cytochrome 450 (CYP) isoenzyme CYP1A2.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 53 | Get Quote |
|
| 5MG | 164 | Get Quote |
|
| 10MG | 238 | Get Quote |
|
| 25MG | 490 | Get Quote |
|
| 50MG | 707 | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
-
Product NameN-desmethyl Olanzapine
-
NoteResearch use only, not for human use.
-
Brief DescriptionN-desmethyl Olanzapine is a metabolite of the atypical antipsychotic compound Olanzapinec, which is formed through the oxidative metabolism of olanzapine by the cytochrome 450 (CYP) isoenzyme CYP1A2.
-
DescriptionN-Desmethylolanzapine is an antipsychotic drug.The formation of N-Desmethylolanzapine correlates with the level and activityof human liver flavin-containing monooxygenase (FMO3). N-Desmethylolanzapinecan be used in the study of antipsychotic drugs .
-
In Vitro——
-
In Vivo——
-
Synonyms——
-
PathwayMetabolic Enzyme/Protease
-
TargetP450
-
RecptorP450 | Drug Metabolite
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number161696-76-0
-
Formula Weight298.41
-
Molecular FormulaC16H18N4S
-
Purity>98% (HPLC)
-
Solubility——
-
SMILESCc1cc2c(Nc3ccccc3N=C2N2CCNCC2)s1
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Ring BJ, et al. Identification of the human cytochromes P450 responsible for the in vitro formation of the major oxidative metabolites of the antipsychotic agent olanzapine. J Pharmacol Exp Ther. 1996 Feb;276(2):658-66.?
molnova catalog
related products
-
Dehydroabiethylamine
Dehydroabiethylamine is an inducer of hepatic CYP2B activity.
-
2,6-Dimethoxyquinone
2, 6-dimethoxy-1, 4-benzoquinone is a member of the class of compounds known as P-benzoquinones.
-
PF-4981517
PF-4981517 (CYP3cide) is a efficient, specific and time-dependent inhibitor of cytochrome P4503A4 (CYP3A4). The IC 50 values for CYP3A activity are 0.03 μM,17 μM, and 71 μM for CYP3A4, CYP3A5, and CYP3A7, respectively.
