Sphingomyelin( —— )

Catalog No. M37952 CAS No. 85187-10-6

COA

Datasheet

HNMR

HPLC

MSDS

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Product Name

Sphingomyelin
Note

Research use only, not for human use.
Brief Description

Sphingomyelin is a natural sphingolipid that existed in animal cell membranes. It implicates the regulation of transmembrane signaling.
Description

Sphingomyelin is a eukaryotic sphingolipid and one of the major constituents of cell membranes and particularly abundant in the myelin sheath that surrounds neuronal axons. Sphingomyelin plays an important role in cell processes, the regulation of inflammatory responses, and signal transduction. Sphingomyelin metabolism is associated with various central nervous system diseases and Niemann–Pick disease.
In Vitro

Sphingomyelin metabolism resulting in the production of various interconvertible bioactive sphingolipids or derivatives such as ceramide, diacylglyceride, and sphingosine-1-phosphate. These bioactive lipids act on their specific targets within the cell and regulate various signal transduction pathways, thereby affecting cellular functions.Sphingomyelin enriched lipid raft mediated cell signaling.
In Vivo

——
Synonyms

——
Pathway

Proteasome/Ubiquitin
Target

Endogenous Metabolite
Recptor

Endogenous Metabolite
Research Area

——
Indication

——

CAS Number

85187-10-6
Formula Weight

731.097
Molecular Formula

C41H83N2O6P
Purity

>98% (HPLC)
Solubility

In Vitro:?Ethanol : 25 mg/mL (Ultrasonic)
SMILES

CCCCCCCCCCCCCCCCCC(=O)N[C@@H](COP([O-])(=O)OCC[N+](C)(C)C)[C@H](O)\C=C\CCCCCCCCCCCCC
Chemical Name

——

1. Chakraborty M, et al. Sphingomyelin and its role in cellular signaling. Adv Exp Med Biol. 2013;991:1-14.?

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