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InhA-IN-3

CAS No. 900701-83-9

InhA-IN-3( —— )

Catalog No. M35482 CAS No. 900701-83-9

InhA-IN-3 (TU13) is a potent inhibitor of Mycobacterium tuberculosis InhA (enoyl ACP reductase) with potential anticancer and antiproliferative activities for the study of Mycobacterium tuberculosis infections.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    InhA-IN-3
  • Note
    Research use only, not for human use.
  • Brief Description
    InhA-IN-3 (TU13) is a potent inhibitor of Mycobacterium tuberculosis InhA (enoyl ACP reductase) with potential anticancer and antiproliferative activities for the study of Mycobacterium tuberculosis infections.
  • Description
    InhA-IN-3 (Compound TU12) is a Mycobacterium tuberculosis InhA (an enoyl ACP-reductase) inhibitor with an IC50 of 17.7 μM.
  • In Vitro
    InhA-IN-3 (Compound TU12) shows antitubercular activity with a MIC of 0.78±0.59 μg/mL against Mycobacterium tuberculosis.
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    GPCR/G Protein
  • Target
    Antibacterial
  • Recptor
    Antibacterial
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    900701-83-9
  • Formula Weight
    321.78
  • Molecular Formula
    C14H12ClN3O2S
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    [O-][N+](=O)C1=CC=C(NC(=S)NCC2=C(Cl)C=CC=C2)C=C1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Do?an ?D, et al. Design and synthesis of thiourea-based derivatives as Mycobacterium tuberculosis growth and enoyl acyl carrier protein reductase (InhA) inhibitors. Eur J Med Chem. 2020 Aug 1;199:112402.?
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