InhA-IN-3( —— )

Catalog No. M35482 CAS No. 900701-83-9

InhA-IN-3 (TU13) is a potent inhibitor of Mycobacterium tuberculosis InhA (enoyl ACP reductase) with potential anticancer and antiproliferative activities for the study of Mycobacterium tuberculosis infections.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

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Biological Information

Product Name

InhA-IN-3
Note

Research use only, not for human use.
Brief Description

InhA-IN-3 (TU13) is a potent inhibitor of Mycobacterium tuberculosis InhA (enoyl ACP reductase) with potential anticancer and antiproliferative activities for the study of Mycobacterium tuberculosis infections.
Description

InhA-IN-3 (Compound TU12) is a Mycobacterium tuberculosis InhA (an enoyl ACP-reductase) inhibitor with an IC50 of 17.7 μM.
In Vitro

InhA-IN-3 (Compound TU12) shows antitubercular activity with a MIC of 0.78±0.59 μg/mL against Mycobacterium tuberculosis.
In Vivo

——
Synonyms

——
Pathway

GPCR/G Protein
Target

Antibacterial
Recptor

Antibacterial
Research Area

——
Indication

——

Chemical Information

CAS Number

900701-83-9
Formula Weight

321.78
Molecular Formula

C14H12ClN3O2S
Purity

>98% (HPLC)
Solubility

——
SMILES

[O-][N+](=O)C1=CC=C(NC(=S)NCC2=C(Cl)C=CC=C2)C=C1
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. Do?an ?D, et al. Design and synthesis of thiourea-based derivatives as Mycobacterium tuberculosis growth and enoyl acyl carrier protein reductase (InhA) inhibitors. Eur J Med Chem. 2020 Aug 1;199:112402.?

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