Monoxerutin( —— )

Catalog No. M34656 CAS No. 23869-24-1

Monoxerutin (MonoHER) is a vasodilator with antioxidant activity that prevents adriamycin-induced cardiotoxicity in mice and is used in the study of acute respiratory syndrome.

Purity : >98% (HPLC)

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Biological Information

Product Name

Monoxerutin
Note

Research use only, not for human use.
Brief Description

Monoxerutin (MonoHER) is a vasodilator with antioxidant activity that prevents adriamycin-induced cardiotoxicity in mice and is used in the study of acute respiratory syndrome.
Description

MonoHER (7-Monohydroxyethylrutoside) is a Carbonyl reductase 1 (CBR1) inhibitor and can be used as a cardioprotective agent. MonoHER inhibits the activity of CBR1 V88 and CBR1 I88 in a concentration-dependent manner.
In Vitro

——
In Vivo

——
Synonyms

——
Pathway

Others
Target

Antioxidant
Recptor

Antioxidant
Research Area

——
Indication

——

Chemical Information

CAS Number

23869-24-1
Formula Weight

654.57
Molecular Formula

C29H34O17
Purity

>98% (HPLC)
Solubility

——
SMILES

O(C1=C(OC=2C(C1=O)=C(O)C=C(OCCO)C2)C3=CC(O)=C(O)C=C3)[C@@H]4O[C@H](CO[C@H]5[C@H](O)[C@H](O)[C@@H](O)[C@H](C)O5)[C@@H](O)[C@H](O)[C@H]4O
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. Gonzalez-Covarrubias V, et al. Inhibition of polymorphic human carbonyl reductase 1 (CBR1) by the cardioprotectant flavonoid 7-monohydroxyethyl rutoside (monoHER). Pharm Res. 2008 Jul;25(7):1730-4.?

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