Clomethiazole( Chlormethiazole | 5-(2-CHLOROETHYL)-4-METHYLTHIAZOLE | Distraneurin )

Catalog No. M24511 CAS No. 533-45-9

Clomethiazole is an orally active GABAA agonist and it is an anticonvulsant agent.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

Size	Price / USD	Stock	Quantity
1 mL x 10 mM in DMSO	43	In Stock
100MG	38	In Stock
200MG	54	In Stock
500MG	89	In Stock
1G	Get Quote	In Stock

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Biological Information

Product Name

Clomethiazole
Note

Research use only, not for human use.
Brief Description

Clomethiazole is an orally active GABAA agonist and it is an anticonvulsant agent.
Description

Clomethiazole is an orally active GABAA agonist and it is an anticonvulsant agent. It also has the potential for treating convulsive status epilepticus. Chlormethiazole inhibits cytochrome P450 isoforms: CYP2A6 and CYP2E1 in human liver microsomes.
In Vitro

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In Vivo

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Synonyms

Chlormethiazole | 5-(2-CHLOROETHYL)-4-METHYLTHIAZOLE | Distraneurin
Pathway

Membrane Transporter/Ion Channel
Target

Other Targets
Recptor

GABAA|CYP2A6|CYP2E1
Research Area

——
Indication

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Chemical Information

CAS Number

533-45-9
Formula Weight

161.65
Molecular Formula

C6H8ClNS
Purity

>98% (HPLC)
Solubility

DMSO : 240 mg/mL?(1484.69 mM;?Need ultrasonic)
SMILES

Cc1c(CCCl)scn1
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1.Nelson RM, et al.Electrophysiological actions of gamma-aminobutyric acid and clomethiazole on recombinant GABA(A) receptors.Eur J Pharmacol. 2002 Oct 11;452(3):255-62.

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