Tyrphostin A1
CAS No. 2826-26-8
Tyrphostin A1( Tyrphostin 1 | AG9 )
Catalog No. M20945 CAS No. 2826-26-8
Tyrphostin A1 is an inhibitor of EGFR tyrosine kinase .
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 28 | In Stock |
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| 10MG | 29 | In Stock |
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| 25MG | 50 | In Stock |
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| 50MG | 71 | In Stock |
|
| 100MG | 91 | In Stock |
|
| 200MG | 133 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameTyrphostin A1
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NoteResearch use only, not for human use.
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Brief DescriptionTyrphostin A1 is an inhibitor of EGFR tyrosine kinase .
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DescriptionTyrphostin A1 is an inhibitor of EGFR tyrosine kinase .
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In Vitro——
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In Vivo——
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SynonymsTyrphostin 1 | AG9
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PathwayAngiogenesis
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TargetEGFR
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RecptorEGFR
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Research Area——
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Indication——
Chemical Information
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CAS Number2826-26-8
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Formula Weight184.19
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Molecular FormulaC11H8N2O
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Purity>98% (HPLC)
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SolubilityDMSO:100 mg/mL (542.92 mM)
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SMILESCOc1ccc(C=C(C#N)C#N)cc1
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Chemical Name2-[(4-Methoxyphenyl)methylidene]propanedinitrile
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
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AG-825
AG-825(Tyrphostin C15) is a selective and competitive ErbB2 inhibitor that inhibits tyrosine phosphorylation with an IC50 value of 0.35 μM.AG-825 (Tyrphostin C15) inhibits HER2 and shows anticancer activity in a mouse xenograft model of breast cancer.
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PF-06459988
PF-06459988 (PF06459988, PF 6459988) is a potent, selective, irreversible EGFR mutants with IC50 of 13, 7, 21 and 90 nM for EGFR L858R-T790M, Del-T790M, L858R, and EGFR Del, respectively.
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Falnidamol
Falnidamol (BIBX 1382) is an orally active, selective EGFR tyrosine kinase inhibitor with an IC50 of 3 nM. It displays >1000-fold lower potency against ErbB2 (IC50=3.4 μM) and other related tyrosine kinases (IC50>10 μM).
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