HA155( CS-963 )

Catalog No. M26244 CAS No. 1312201-00-5

HA155 selectively and potently inhibits autotaxin with an IC50 of 5.7 nM.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

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Biological Information

Product Name

HA155
Note

Research use only, not for human use.
Brief Description

HA155 selectively and potently inhibits autotaxin with an IC50 of 5.7 nM.
Description

HA155 selectively and potently inhibits autotaxin with an IC50 of 5.7 nM.(In Vitro):HA155 completely attenuates the thrombin-mediated increase in platelet-derived LPA dose-dependently .HA155 is an ATX inhibitor by binding to the ATX active site .
In Vitro

HA-155 inhibits ATX by binding to the ATX active site.HA155 completely attenuates the thrombin-mediated increase in platelet-derived LPA in a dose-dependent manner.
In Vivo

——
Synonyms

CS-963
Pathway

Angiogenesis
Target

PDE
Recptor

Antibacterial
Research Area

——
Indication

——

Chemical Information

CAS Number

1312201-00-5
Formula Weight

463.29
Molecular Formula

C24H19BFNO5S
Purity

>98% (HPLC)
Solubility

In Vitro:?DMSO : 10 mg/mL (21.58 mM)
SMILES

O=C1N(CC2=CC=C(F)C=C2)C(S/C1=C\C3=CC=C(OCC4=CC=C(B(O)O)C=C4)C=C3)=O.[(Z)]
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1.Guo B, et al. Clinical Pharmacokinetics of Levornidazole in Elderly Subjects and Dosing Regimen Evaluation Using Pharmacokinetic/Pharmacodynamic Analysis. Clin Ther. 2017 Jul;39(7):1336-1346.

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