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Glabrol

CAS No. 59870-65-4

Glabrol( —— )

Catalog No. M21683 CAS No. 59870-65-4

Glabrol is a PTP1B inhibitor it is also a CYP1B1 inhibitor it shows inhibition of CYP1B1 in live cell assay with the IC50 value of 15uM.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

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Biological Information

Product Name

Glabrol
Note

Research use only, not for human use.
Brief Description

Glabrol is a PTP1B inhibitor it is also a CYP1B1 inhibitor it shows inhibition of CYP1B1 in live cell assay with the IC50 value of 15uM.
Description

Glabrol is a PTP1B inhibitor it is also a CYP1B1 inhibitor it shows inhibition of CYP1B1 in live cell assay with the IC50 value of 15uM.
In Vitro

Glabrol (Compound 1) decreases cholesteryl ester formation with an IC50 value of 26.0 μM in HepG2 cells.
In Vivo

——
Synonyms

——
Pathway

Metabolic Enzyme/Protease
Target

P450
Recptor

P450|NO Synthase|NF-κB
Research Area

——
Indication

——

Chemical Information

CAS Number

59870-65-4
Formula Weight

392.49
Molecular Formula

C25H28O4
Purity

>98% (HPLC)
Solubility

In Vitro:?DMSO : 100 mg/mL (254.78 mM)
SMILES

CC(C)=CCc(cc([C@H](C1)Oc(c(CC=C(C)C)c(cc2)O)c2C1=O)cc1)c1O
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1.Screening for bioactive natural products from a 67-compound library of Glycyrrhiza inflata.Bioorg Med Chem. 2017 Jul 15;25(14):3706-3713.

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