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Fiacitabine

CAS No. 69123-90-6

Fiacitabine( NSC-382097 | FIAC )

Catalog No. M15648 CAS No. 69123-90-6

A synthesized pyrimidine analog that is a potent and selective anti-herpesvirus agent; suppresses various strains of HSV1 and HSV2 with IC90 of 2.5 nM and 12.6 nM, respectively.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Fiacitabine
  • Note
    Research use only, not for human use.
  • Brief Description
    A synthesized pyrimidine analog that is a potent and selective anti-herpesvirus agent; suppresses various strains of HSV1 and HSV2 with IC90 of 2.5 nM and 12.6 nM, respectively.
  • Description
    A synthesized pyrimidine analog that is a potent and selective anti-herpesvirus agent; suppresses various strains of HSV1 and HSV2 with IC90 of 2.5 nM and 12.6 nM, respectively, shows minimal cytotoxicity; more potent than arabinosylcytosine, iododeoxyuridine, and arabinosyladenine.HSV Infection Phase 2 Discontinued.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    NSC-382097 | FIAC
  • Pathway
    Microbiology/Virology
  • Target
    HSV
  • Recptor
    HSV
  • Research Area
    Infection
  • Indication
    HSV Infection

Chemical Information

  • CAS Number
    69123-90-6
  • Formula Weight
    371.1042
  • Molecular Formula
    C9H11FIN3O4
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO: ≥ 37 mg/mL
  • SMILES
    O=C1N=C(N)C(I)=CN1[C@H]2[C@@H](F)[C@@H]([C@@H](CO)O2)O
  • Chemical Name
    2(1H)-Pyrimidinone, 4-amino-1-(2-deoxy-2-fluoro-.beta.-D-arabinofuranosyl)-5-iodo-

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Lopez C, et al. Antimicrob Agents Chemother. 1980 May;17(5):803-6. 2. Allaudeen HS, et al. J Biol Chem. 1982 Oct 25;257(20):11879-82. 3. Schinazi RF, et al. Antimicrob Agents Chemother. 1983 Jul;24(1):95-103.
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