Cart
sales@molnova.com
Home - Products - Microbiology/Virology - HSV - FV-100

FV-100

CAS No. 956483-03-7

FV-100( Valnivudine | FV100 | CF-1743 )

Catalog No. M16827 CAS No. 956483-03-7

FV-100 (Valnivudine, CF-1743) is a potent, selective, bicyclic nucleoside analogue inhibitor of varicella zoster virus (VZV) with EC50 of subnanomolar range in vitro.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 335 In Stock
10MG 560 In Stock
25MG 870 In Stock
50MG 1152 In Stock
100MG 1575 In Stock
500MG 3168 In Stock
1G Get Quote In Stock
Get Quotation Bulk Inquiry Add to Cart

Biological Information

  • Product Name
    FV-100
  • Note
    Research use only, not for human use.
  • Brief Description
    FV-100 (Valnivudine, CF-1743) is a potent, selective, bicyclic nucleoside analogue inhibitor of varicella zoster virus (VZV) with EC50 of subnanomolar range in vitro.
  • Description
    FV-100 (Valnivudine, CF-1743) is a potent, selective, bicyclic nucleoside analogue inhibitor of varicella zoster virus (VZV) with EC50 of subnanomolar range in vitro.HSV Infection Phase 3 Clinical.
  • In Vitro
    FV-100 is intensely fluorescent when illuminated by wavelengths of 340-380 nm.FV-100 (1 h) produces a different distribution in HeLa cells.
  • In Vivo
    FV-100 (50-500 mg/kg; p.o.) does not induce biologically relevant respiratory changes or any apparent neuropharmacological effects in rats.
  • Synonyms
    Valnivudine | FV100 | CF-1743
  • Pathway
    Microbiology/Virology
  • Target
    HSV
  • Recptor
    HSV
  • Research Area
    Infection
  • Indication
    HSV Infection

Chemical Information

  • CAS Number
    956483-03-7
  • Formula Weight
    548.077
  • Molecular Formula
    C28H38ClN3O6
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 100 mg/mL (187.25 mM)
  • SMILES
    CCCCCC1=CC=C(C=C1)C2=CC3=CN(C(=O)N=C3O2)C4CC(C(O4)COC(=O)C(C(C)C)N)O.Cl
  • Chemical Name
    ((2R,3S,5R)-3-hydroxy-5-(2-oxo-6-(4-pentylphenyl)furo[2,3-d]pyrimidin-3(2H)-yl)tetrahydrofuran-2-yl)methyl (S)-3-amino-4-methylpentanoate hydrochloride

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. McGuigan C, et al. J Antimicrob Chemother. 2007 Dec;60(6):1316-30. 2. Pentikis HS, et al. Antimicrob Agents Chemother. 2011 Jun;55(6):2847-54. 3. Migliore M. Antivir Chem Chemother. 2010 Jan 5;20(3):107-15. 4. Tyring SK, et al. J Med Virol. 2017 Jul;89(7):1255-1264.
Calculator

Molecular Weight Calculator

Dilution Calculator

Molarity Calculator

molnova catalog
related products

  • Aquacycline

    Oxytetracycline (OTC) is a broad-spectrum antibiotic that acts by inhibiting protein synthesis in bacteria. Oxytetracycline prevents the binding from aminoacil-tRNA to the complex m-ribosomal RNA. Oxytetracycline also possesses anti-HSV-1 activity.

  • nerolidol

    Nerolidol shows sedative effects in animals, oxidative process plays a crucial role on neuronal pathological consequence.

  • Histone H4 (2-21)

    Histone H4 (2-21) is the core histones associated with chromatinization of herpes simplex virus 1 (HSV-1) genomes.

Sign In Join Free