Cart
sales@molnova.com
FASN-IN-3
CAS No. 2097262-60-5
FASN-IN-3( —— )
Catalog No. M23946 CAS No. 2097262-60-5
FASN-IN-3 is an inhibitor of fatty acid synthase (FASN).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 260 | In Stock |
|
| 10MG | 430 | In Stock |
|
| 25MG | 710 | In Stock |
|
| 50MG | 972 | In Stock |
|
| 100MG | 1332 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameFASN-IN-3
-
NoteResearch use only, not for human use.
-
Brief DescriptionFASN-IN-3 is an inhibitor of fatty acid synthase (FASN).
-
DescriptionFASN-IN-3 is an inhibitor of fatty acid synthase (FASN).
-
In VitroHuman PBMC and monocytes in cell cultures are stimulated with lipopolysaccharide (LPS), a Toll 4 receptor agonist, or lipoteichoic acid (LTA), a Toll 2 receptor agonist. Stimulation with either LPS or LTA plus DMSO, the solvent for FASN-IN-3 (Compound 242A), results in secretion of IL-1 beta. FASN inhibitor 1 treatment of PBMC, which is a mixed population of mononuclear cells including both lymphocytes and monocytes, reduces the level of IL-1 beta resulting from either LPS or LTA stimulation. For monocytes, FASN-IN-3 treatment reduces the level of IL-1 beta resulting from LTA stimulation whereas there is only a slight reduction after LPS stimulation.
-
In Vivo——
-
Synonyms——
-
PathwayMetabolic Enzyme/Protease
-
TargetFatty Acid Synthase
-
RecptorFASN
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number2097262-60-5
-
Formula Weight384.47
-
Molecular FormulaC24H24N4O
-
Purity>98% (HPLC)
-
SolubilityDMSO:33.33 mg/mL?(86.69 mM;?ultrasonic and warming and heat to 80°C)
-
SMILESCc1n[nH]c(c1C)-c1cc(C(=O)N2CC(C2)c2ccc(cc2)C#N)c(C)cc1C
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
-
TVB-3664
TVB-3664 significantly decreases tubulin palmitoylation and mRNA expression. TVB-3664 is a reversible and highly bioavailable fatty acid synthase inhibitor (IC50: 18 nM and 12 nM for human and mouse cell palmitate synthesis, respectively).
-
ACSS2-IN-2
ACSS2-IN-2 is an inhibitor of acyl-CoA synthetase short-chain family member 2 (ACSS2). ACSS2-IN-2 can inhibit ACSS2 activity with an IC50 value of 3.8 nM. ACSS2-IN-2 can be used for the research of several diseases, such as viral infection, metabolic disorders, neuropsychiatric diseases, inflammatory/autoimmune conditions and cancer.
-
Orlistat
Orlistat is a drug designed to treat obesity. Its primary function is preventing the absorption of fats from the human diet, thereby reducing caloric intake.
