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Home - Products - Metabolic Enzyme/Protease - P450 - Dehydroabiethylamine

Dehydroabiethylamine

CAS No. 1446-61-3

Dehydroabiethylamine( Leelamine | Leelamine free base | NSC-2955 | NSC 2955 | NSC2955 )

Catalog No. M27157 CAS No. 1446-61-3

Dehydroabiethylamine is an inducer of hepatic CYP2B activity.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Dehydroabiethylamine
  • Note
    Research use only, not for human use.
  • Brief Description
    Dehydroabiethylamine is an inducer of hepatic CYP2B activity.
  • Description
    Dehydroabiethylamine is an inducer of hepatic CYP2B activity. Dehydroabiethylamine inhibits pyruvate dehydrogenase kinases (PDKs) and intracellular cholesterol transport with anti-tumor activity.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    Leelamine | Leelamine free base | NSC-2955 | NSC 2955 | NSC2955
  • Pathway
    Metabolic Enzyme/Protease
  • Target
    P450
  • Recptor
    NF-κB
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1446-61-3
  • Formula Weight
    285.475
  • Molecular Formula
    C20H31N
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 100 mg/mL (350.30 mM)
  • SMILES
    CC(C)c1ccc2c(CC[C@H]3[C@](C)(CN)CCC[C@]23C)c1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Okolotowicz KJ, et al. Selective benzimidazole inhibitors of the antigen receptor-mediated NF-kappaB activationpathway. Bioorg Med Chem. 2010 Mar 1;18(5):1918-24.
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