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DB04760
CAS No. 544678-85-5
DB04760( —— )
Catalog No. M33333 CAS No. 544678-85-5
DB04760 is a highly selective, non-zinc-chelating inhibitor of MMP-13 (IC50: 8 nM). DB04760 obviously decreases paclitaxel neurotoxicity and has anticancer activity.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 122 | Get Quote |
|
| 5MG | 217 | Get Quote |
|
| 10MG | 326 | Get Quote |
|
| 25MG | 533 | Get Quote |
|
| 50MG | 763 | Get Quote |
|
| 100MG | 1035 | Get Quote |
|
| 500MG | 2052 | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
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Product NameDB04760
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NoteResearch use only, not for human use.
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Brief DescriptionDB04760 is a highly selective, non-zinc-chelating inhibitor of MMP-13 (IC50: 8 nM). DB04760 obviously decreases paclitaxel neurotoxicity and has anticancer activity.
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DescriptionDB04760 (compound 4) is a potent, highly selective, non-zinc-chelating MMP-13 inhibitor with an IC50 of 8 nM. DB04760 significantly reduces paclitaxel neurotoxicity and has anticancer activity.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayMetabolic Enzyme/Protease
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TargetMMP
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RecptorMMP
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Research Area——
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Indication——
Chemical Information
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CAS Number544678-85-5
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Formula Weight410.42
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Molecular FormulaC22H20F2N4O2
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 100 mg/mL (243.65 mM; Ultrasonic )
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SMILESCc1cc(CNC(=O)c2cc(ncn2)C(=O)NCc2ccc(F)c(C)c2)ccc1F
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Engel CK, et al. Structural basis for the highly selective inhibition of MMP-13. Chem Biol. 2005 Feb;12(2):181-9.?
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