Cordycepin

CAS No. 73-03-0

Cordycepin( 3'-Deoxyadenosine | NSC 63984 | NSC 401022 )

Catalog No. M15794 CAS No. 73-03-0

Cordycepin is a potent inhibitor of IL-1β-induced chemokine production and MMP expression and strongly blocks the p38/JNK/AP-1 signalling pathway in RASFs.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
10MG 39 In Stock
25MG 88 In Stock
50MG 152 In Stock
100MG 248 In Stock
500MG 606 In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    Cordycepin
  • Note
    Research use only, not for human use.
  • Brief Description
    Cordycepin is a potent inhibitor of IL-1β-induced chemokine production and MMP expression and strongly blocks the p38/JNK/AP-1 signalling pathway in RASFs.
  • Description
    Cordycepin is a potent inhibitor of IL-1β-induced chemokine production and MMP expression and strongly blocks the p38/JNK/AP-1 signalling pathway in RASFs. The effect of Cordycepin on cellular toxicity of RASFs is assessed using MTT assay. Treatment of RASFs with Cordycepin (50 μM or 100 μM) for 24 h does not cause any significant change in cell viability. However, cell viability is slightly decreased when cells are incubated with 100 μM Cordycepin for 48 h.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    3'-Deoxyadenosine | NSC 63984 | NSC 401022
  • Pathway
    Metabolic Enzyme/Protease
  • Target
    MMP
  • Recptor
    TNF-α
  • Research Area
    Infection
  • Indication
    ——

Chemical Information

  • CAS Number
    73-03-0
  • Formula Weight
    251.24
  • Molecular Formula
    C10H13N5O3
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO: Soluble
  • SMILES
    O[C@H]1[C@H](N2C=NC3=C(N)N=CN=C23)O[C@H](CO)C1
  • Chemical Name
    (2R,3R,5S)-2-(6-amino-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3-ol

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Noh EM, et al. Cordycepin inhibits IL-1beta-induced MMP-1 and MMP-3 expression in rheumatoid arthritis synovial fibroblasts. Rheumatology (Oxford). 2009 Jan;48(1):45-8.
molnova catalog
related products
  • Bacoside A

    Bacoside A has a possible anticancer activity that could be inducing cell cycle arrest and apoptosis through Notch pathway in GBM in vitro.

  • isomer-CM 352

    isomer-CM 352 is a metalase inhibitor that can be used to slow brain damage.

  • GI 254023X

    GI254023X is a potent MMP9 and ADAM10 inhibitor (IC50s: 2.5 and 5.3 nM) with 100-fold selectivity for the α-secretase ADAM10 over ADAM17 (TACE).