Chelerythrine( —— )

Catalog No. M18448 CAS No. 34316-15-9

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Datasheet

HNMR

HPLC

MSDS

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Product Name

Chelerythrine
Note

Research use only, not for human use.
Brief Description

Chelerythrine is a well-known protein kinase C inhibitor.
Description

Chelerythrine may have antimanic effect . Chelerythrine can inhibit telomerase activity. Chelerythrine is a well-known protein kinase C inhibitor.Chelerythrine has potential antiproliferative and antitumor effects.
In Vitro

Western Blot Analysis Cell Line:A549 and NCI-H1299 cells Concentration:10, 15, 20 μM Incubation Time:24 h Result:Induced expression of LC3-II in a beclin 1-dependent way.
In Vivo

Animal Model:Unilateral ureteral obstruction (UUO) induced neonatal ratsDosage:5 mg/kg Administration:i.p., daily Result:Attenuated kidney injury (Increased kidney weight and restored renal function).Inhibited UUO-induced upregulated kidney injury molecule-1 expression, apoptosis, and renal fibrosis.
Synonyms

——
Pathway

Angiogenesis
Target

PDE
Recptor

Others
Research Area

Cancer
Indication

——

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