Caulophyllogenin( Segetalic acid )

Catalog No. M29110 CAS No. 52936-64-8

COA

Datasheet

HNMR

HPLC

MSDS

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Product Name

Caulophyllogenin
Note

Research use only, not for human use.
Brief Description

Caulophyllogenin is a partial PPARγ agonist (EC50?=?12.6?μM) derived from the stem bark of Kalopanax pictus (Araliaceae).
Description

Caulophyllogenin is a partial PPARγ agonist (EC50?=?12.6?μM) derived from the stem bark of Kalopanax pictus (Araliaceae). Caulophyllogenin inhibits pro-inflammatory cytokine secretion and can be used in studies about the prevention and treatment of inflammatory diseases, type-2 diabetes, obesity and metabolic syndrome.(In Vitro):Caulophyllogenin inhibits IL-12 p40, IL-6, and TNF-α with IC50s ranging from 3.3 to 20.0 μM.
In Vitro

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In Vivo

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Synonyms

Segetalic acid
Pathway

Apoptosis
Target

IL Receptor
Recptor

IL Receptor
Research Area

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Indication

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CAS Number

52936-64-8
Formula Weight

488.709
Molecular Formula

C30H48O5
Purity

>98% (HPLC)
Solubility

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SMILES

[H][C@@]12CC(C)(C)CC[C@@]1([C@H](O)C[C@]1(C)C2=CC[C@]2([H])[C@@]3(C)CC[C@H](O)[C@@](C)(CO)[C@]3([H])CC[C@@]12C)C(O)=O
Chemical Name

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