Ac-DEVD-AMC( AC-ASP-MET-GLN-ASP-7-AMINO-4-METHYLCOUMARIN | AC-ASP-MET-GLN-ASP-AMC )

Catalog No. M27032 CAS No. 169332-61-0

COA

Datasheet

HNMR

HPLC

MSDS

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Product Name

Ac-DEVD-AMC
Note

Research use only, not for human use.
Brief Description

Ac-DEVD-AMC is the substrate of Caspase-3 .
Description

Ac-DEVD-AMC is the substrate of Caspase-3 .(In Vitro):The AMC moiety is highest at 2 h with an area?of 5.6±1.8, the AMC peak area for Ac-DEVD-AMC incubated without a lung specimen (substrate alone) for 6 h is relatively small . Ac-DEVD-AMC can be used to monitor intracellular caspase-3 activity.
In Vitro

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In Vivo

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Synonyms

AC-ASP-MET-GLN-ASP-7-AMINO-4-METHYLCOUMARIN | AC-ASP-MET-GLN-ASP-AMC
Pathway

Apoptosis
Target

Caspase
Recptor

AMPA
Research Area

——
Indication

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CAS Number

169332-61-0
Formula Weight

675.648
Molecular Formula

C30H37N5O13
Purity

>98% (HPLC)
Solubility

In Vitro:?H2O : 0.67 mg/mL (0.99 mM)
SMILES

CC(C)[C@H](NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC(O)=O)NC(C)=O)C(=O)N[C@@H](CC(O)=O)C(=O)Nc1ccc2c(C)cc(=O)oc2c1
Chemical Name

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1.BERRY CYNTHIA G B (US), et al. AZABENZIMIDAZOLES AND THEIR USE AS AMPA RECEPTOR MODULATORS. Patent. WO2016176460.

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