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ACT-389949
CAS No. 1258417-54-7
ACT-389949( —— )
Catalog No. M23429 CAS No. 1258417-54-7
ACT-389949 is a potent and selective agonist of formyl peptide receptor type 2 (FPR2)/Lipoxin A4 receptor (ALX), with an EC50 of 3 nM for FPR2/ALX internalization into monocytes.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 311 | In Stock |
|
| 10MG | 441 | In Stock |
|
| 25MG | 707 | In Stock |
|
| 50MG | 981 | In Stock |
|
| 100MG | 1332 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
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| 1G | Get Quote | In Stock |
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Biological Information
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Product NameACT-389949
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NoteResearch use only, not for human use.
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Brief DescriptionACT-389949 is a potent and selective agonist of formyl peptide receptor type 2 (FPR2)/Lipoxin A4 receptor (ALX), with an EC50 of 3 nM for FPR2/ALX internalization into monocytes.
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DescriptionACT-389949 is a potent and selective agonist of formyl peptide receptor type 2 (FPR2)/Lipoxin A4 receptor (ALX), with an EC50 of 3 nM for FPR2/ALX internalization into monocytes. It has the potential for the treatment of inflammatory disorders.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayOthers
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TargetOther Targets
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RecptorFPR2/ALX
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Research Area——
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Indication——
Chemical Information
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CAS Number1258417-54-7
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Formula Weight428.39
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Molecular FormulaC20H18F2N6O3
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Purity>98% (HPLC)
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SolubilityDMSO:10 mg/mL (23.34 mM; ultrasonic and adjust pH to 1 with HCl)
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SMILESO=C(NC1=NN(N=C1)CC2=NC(C(F)(C)F)=CO2)C3=C(OC(C)=N3)C4=CC=CC(C)=C4
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
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S6-1
S6 peptide is a potentially important lamin kinase. S6 peptide is involved in the process of cardiac hypertrophy induced by mechanical loading. S6 peptide can be activated by many kinds of growth factors.
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Runcaciguat
Runcaciguat is a soluble guanylate cyclase stimulator. Runcaciguat combines with selective partial adenosine A1 receptor agonists and can be used in studies about cardiovascular and renal diseases.
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Prosaptide TX14(A)
Potent GPR37L1 and GPR37 agonist (EC50 values are 5 and 7 nM, respectively). Stimulates signaling through pertussis toxin-sensitive G proteins. Stimulates ERK phosphorylation. Protects against cellular stress. Promotes myelin lipid synthesis and prolongs cell survival in both Schwann cells and oligodendrocytes; neuroprotective and glioprotective.
