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12R-LOX-IN-2

CAS No. 3026677-37-9

12R-LOX-IN-2( —— )

Catalog No. M37042 CAS No. 3026677-37-9

12R-LOX-IN-2 is an inhibitor of 12R-lipoxygenase (12R-LOX).12R-LOX-IN-2 inhibits imiquimod (IMQ)-induced hyperproliferation of psoriatic keratinocytes and inhibits colony formation.

Purity : >98% (HPLC)

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Biological Information

Product Name

12R-LOX-IN-2
Note

Research use only, not for human use.
Brief Description

12R-LOX-IN-2 is an inhibitor of 12R-lipoxygenase (12R-LOX).12R-LOX-IN-2 inhibits imiquimod (IMQ)-induced hyperproliferation of psoriatic keratinocytes and inhibits colony formation.
Description

12R-LOX-IN-2 is an inhibitor of 12R-lipoxygenase (12R-LOX).12R-LOX-IN-2 inhibits imiquimod (IMQ)-induced hyperproliferation of psoriatic keratinocytes and inhibits colony formation.12R-LOX-IN-2 also decreases the protein level of Ki67 and the mRNA expression of IL-17A in IMQ-induced cells. 12R-LOX-IN-2 may be useful in the study of psoriasis and other skin-associated inflammatory diseases.
In Vitro

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In Vivo

——
Synonyms

——
Pathway

Immunology/Inflammation
Target

Lipoxygenase
Recptor

Lipoxygenase
Research Area

——
Indication

——

Chemical Information

CAS Number

3026677-37-9
Formula Weight

271.31
Molecular Formula

C19H13NO
Purity

>98% (HPLC)
Solubility

——
SMILES

OC=1C=CC(C2=NC=3C=CC=CC3C=C2)=C4C=CC=CC14
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

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